Trends in coordination of rhenium organometallic complexes in the Protein Data Bank

A Brink, FJF Jacobs, JR Helliwell
IUCrJ 9 (2022) 180-193.
Science Published: (Mar/2024)

Radiopharmaceutical development has similar overall characteristics to any biomedical drug development requiring a compound's stability, aqueous solubility and selectivity to a specific disease site. However, organometallic complexes containing 188/186Re or 99mTc involve a d-block transition-metal radioactive isotope and therefore bring additional factors such as metal oxidation states, isotope purity and half life into play. This topical review is focused on the development of …

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